For the first time in his career, All-Pro defensive tackle Aaron Donald will be out with the Los Angeles Rams due to injury.

The Rams will host the Seattle Seahawks, but will be without Donald because of a sprained ankle he suffered against the Kansas City Chiefs in Sunday’s loss.

A high ankle sprain is a difficult injury to manage, so Donald may be asked to sit out more than just this week. He is considered week by week, according to head coach Sean McVay.

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Los Angeles Rams defensive tackle Aaron Donald, left, celebrates after a sack as defensive tackle Greg Gaines looks on during the first half of a game against the San Francisco 49ers on October 30, 2022 in Inglewood, California.
(AP Photo/Gregory Bull)

His durability has helped Donald become a three-time Defensive Player of the Year and a seven-time All-Pro.

Since breaking into the league with the St. Louis Rams as the 13th pick in the 2014 NFL Draft, Donald has been the epitome of good health in the NFL.

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Donald had a 20.5-sack season in 2018 that led to the Defensive Player of the Year award. He also won that award in 2017 with 11 sacks in 14 games.

Los Angeles Rams defensive end Aaron Donald smiles in practice on July 30, 2022 in Irvine, California.

Los Angeles Rams defensive end Aaron Donald smiles in practice on July 30, 2022 in Irvine, California.
(AP Photo/Mark J. Terrill)

Donald’s injury adds to a disappointing season for the Rams. At 3-8, the Rams have gotten off to the worst start of any team in 11 games since winning a Super Bowl.

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Multiple key starters, including wide receiver Cooper Kupp, have been lost during the season, and McVay is testing Bryce Perkins at quarterback to see what the future holds for the Rams.

That future includes Donald at least through the 2025 season after he signed a three-year, $95 million deal that was fully guaranteed heading into this 2022-23 season.

Los Angeles Rams defensive end Aaron Donald walks off the field after a loss to the New York Jets in Inglewood, California on December 20, 2020.

Los Angeles Rams defensive end Aaron Donald walks off the field after a loss to the New York Jets in Inglewood, California on December 20, 2020.
(AP Photo/Jae C. Hong, File)

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In 11 games this season, Donald has five sacks, 10 tackles for loss and 40 total tackles with 11 quarterback hits and a forced fumble.